# Welcome to NLSAM’s documentation!¶

This is the documentation detailing the internal of the non local spatial and angular matching (NLSAM) denoising algorithm for diffusion MRI, which is available at https://github.com/samuelstjean/nlsam.

You can find the original paper and full details of the algorithm as presented in

St-Jean, S., Coupé, P., & Descoteaux, M. (2016)
"Non Local Spatial and Angular Matching :
Enabling higher spatial resolution diffusion MRI datasets through adaptive denoising."
Medical Image Analysis, 32(2016), 115–130.


Which you can grab a copy from the publisher website or from arxiv.

You an find below the documentation for each modules and a few instructions on topics such as noise estimation and detailed installation instructions.